SCHEMBL14949293

SCHEMBL14949293

COCc1cc(CO)c2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.46
AKR1B1 P15121 1/20 0.41
ATM Q13315 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NQO2 P16083 1/20 0.36
TACR1 P25103 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MPI P34949 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15978723 0.89 F2 (0.48) F2AKR1B1ATMMEN1KMT2A
SCHEMBL19449781 0.88 F2 (0.45) F2AKR1B1ATMMEN1KMT2A
SCHEMBL1068764 0.83 AKR1B1 (0.43) F2AKR1B1MEN1KMT2AKDM4E
SCHEMBL3044042 0.81 TSHR (0.42) F2AKR1B1MEN1KMT2ANQO2
SCHEMBL17919574 0.80 CYP1A2 (0.48) F2MEN1KMT2AALDH1A1MAPT
SCHEMBL4349485 0.76 TACR1 (0.41) F2AKR1B1ATMMEN1KMT2A
SCHEMBL8965862 0.75 AKR1B1 (0.50) AKR1B1MEN1KMT2ANQO2
SCHEMBL21822102 0.75 CALM1 (0.44)
SCHEMBL4202279 0.74 LMNA (0.43) AKR1B1ATMMEN1KMT2ALMNA
SCHEMBL4372632 0.74 MAPT (0.40) MEN1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013069812-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM, MASK BLANK AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2013-05-16 WO disclosed