Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | Q9HBH1 | 1/20 | 0.37 | |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950214 | 1.00 | FURIN (0.41) | FURINMMP3KLKB1SIRT2SIRT1 | |
| SCHEMBL17752524 | 0.83 | CTSL (0.43) | FURINMMP3KLKB1SIRT2SIRT1 | |
| SCHEMBL15699830 | 0.81 | SIRT5 (0.39) | FURINMMP3SIRT2SIRT1SIRT3 | |
| SCHEMBL21162808 | 0.81 | CTSL (0.38) | FURINMMP3SIRT1CPB2 | |
| SCHEMBL16156452 | 0.79 | SIRT2 (0.42) | FURINSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL18556695 | 0.78 | SIRT2 (0.42) | FURINSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL24390289 | 0.77 | SIRT1 (0.45) | FURINMMP3KLKB1SIRT2SIRT1 | |
| SCHEMBL26033422 | 0.77 | SIRT1 (0.45) | FURINMMP3KLKB1SIRT2SIRT1 | |
| SCHEMBL26017207 | 0.77 | MMP3 (0.43) | FURINMMP3KLKB1SIRT2SIRT1 | |
| SCHEMBL24906651 | 0.77 | SIRT1 (0.45) | FURINMMP3KLKB1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067597-A1 | IMMUNOMODULATORY CONJUGATES | ASCEND BIOPHARMACEUTICALS PTY LTD (AU) | 2013-05-16 | — | — | WO | disclosed |