Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 6/20 | 0.32 |
| ▸ | RARA | P10276 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931037 | 0.84 | HDAC4 (0.39) | ROCK2GABRA1GABRB2SOAT2MYC | |
| SCHEMBL16050486 | 0.80 | FABP3 (0.41) | ROCK2GABRA1GABRB2SOAT2MYC | |
| SCHEMBL14929520 | 0.80 | ROCK2 (0.35) | ROCK2GABRA1GABRB2SOAT2MYC | |
| SCHEMBL16765785 | 0.79 | HDAC4 (0.45) | HDAC4HDAC8 | |
| SCHEMBL16050488 | 0.77 | GABRA1 (0.52) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL30317598 | 0.77 | ROCK2 (0.39) | ROCK2GABRA1GABRB2SOAT2MYC | |
| SCHEMBL7124077 | 0.77 | ROCK2 (0.39) | ROCK2GABRA1GABRB2SOAT2MYC | |
| SCHEMBL14125007 | 0.75 | ROCK2 (0.33) | ROCK2GABRA1GABRB2SOAT2MYC | |
| Lithium Ion SCHEMBL17203679 | 0.75 | ROCK2 (0.38) | ROCK2GABRA1GABRB2SOAT2MYC | |
| Hydrochloric Acid SCHEMBL21331878 | 0.75 | ROCK2 (0.38) | ROCK2GABRA1GABRB2SOAT2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013070725-A1 | TUNGSTEN OXO ALKYLIDENE COMPLEXES FOR Z SELECTIVE OLEFIN METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-16 | — | — | WO | disclosed |