SCHEMBL16050488

SCHEMBL16050488

CC(C)c1cc(C(C)C)c(-c2cccc(-c3c(C(C)C)cc(C(C)C)cc3C(C)C)c2O)c(C(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 7/20 0.52
GABRB2 P47870 4/20 0.52
GABRB1 P18505 5/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CYP3A4 P08684 3/20 0.48
CYP1A2 P05177 3/20 0.48
HPGD P15428 2/20 0.48
HIF1A Q16665 2/20 0.48
FAAH O00519 1/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 1/20 0.48
GABRG2 P18507 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
HTR2C P28335 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
HTR2B P41595 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28126975 0.98 GABRA1 (0.50) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL17206281 0.84 GABRA1 (0.62) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL7715672 0.83 GABRA1 (0.50) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL14327770 0.83 GPR84 (0.39) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL30777601 0.82 GABRA1 (0.46) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL30317598 0.81 ROCK2 (0.39) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL16050486 0.81 FABP3 (0.41) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL7124077 0.81 ROCK2 (0.39) GABRA1GABRB2GABRB1CA1CA2
Hydrochloric Acid SCHEMBL21331878 0.79 ROCK2 (0.38) GABRA1GABRB2GABRB1CA1CA2
Lithium Ion SCHEMBL17203679 0.79 ROCK2 (0.38) GABRA1GABRB2GABRB1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749674-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-12-16 EP claimed
US-20200369697-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2020-11-26 US claimed
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP claimed
WO-2019157376-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-08-15 WO claimed
US-10343153-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2019-07-09 US claimed
CN-105555402-B Metathesis catalyst and reaction using the same 西莫有限公司 2019-03-22 CN claimed
CN-105555402-A Metathesis catalyst and reaction using the same XIMO AG 2016-05-04 CN claimed
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2016-02-04 US claimed
EP-2969204-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XiMo AG (CH) 2016-01-20 EP claimed
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2014-10-16 US claimed
WO-2014139679-A2 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XIMO AG (CH) 2014-09-18 WO claimed
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2023-10-10 US disclosed
EP-4234522-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2023-08-30 EP disclosed
EP-3377465-B1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI INC (US) 2023-08-02 EP disclosed
WO-2023132366-A1 CYCLOPENTENE RECOVERY METHOD 日本ゼオン株式会社 2023-07-13 WO disclosed
CN-105555402-A Metathesis catalyst and reaction using the same XIMO AG 2016-05-04 CN disclosed
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2016-02-04 US disclosed
EP-2969204-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XiMo AG (CH) 2016-01-20 EP disclosed
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2014-10-16 US disclosed
WO-2014139679-A2 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XIMO AG (CH) 2014-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10343153-B2 Metathesis catalysts and reactions using the catalysts MSMO1, SQLE, MOGAT2 GABRA1 4062/4885GABRB2 4126/4885GABRB1 4099/4885
US-20200369697-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MSRB3, MMAB, CYB5R3 GABRA1 2670/4885GABRB2 2674/4885GABRB1 2356/4885
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, PYM1, SQLE GABRA1 4615/4885GABRB2 4647/4885GABRB1 4589/4885
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, SQLE, PYM1 GABRA1 4622/4885GABRB2 4655/4885GABRB1 4589/4885
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 GABRA1 4065/4885GABRB2 2899/4885GABRB1 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.