Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | FABP3 | P05413 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438073 | 0.85 | GABRA1 (0.38) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| SCHEMBL3181087 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2CA1CA2CYP3A4 | |
| SCHEMBL30317598 | 0.81 | ROCK2 (0.39) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| SCHEMBL16050488 | 0.81 | GABRA1 (0.52) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| SCHEMBL16050486 | 0.81 | FABP3 (0.41) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| SCHEMBL28126975 | 0.79 | GABRA1 (0.50) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| Lithium Ion SCHEMBL17203679 | 0.79 | ROCK2 (0.38) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| Hydrochloric Acid SCHEMBL21331878 | 0.79 | ROCK2 (0.38) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| SCHEMBL14931037 | 0.78 | HDAC4 (0.39) | ROCK2GABRA1GABRB2FABP4FABP3 | |
| SCHEMBL28926436 | 0.77 | LMNA (0.44) | ROCK2GABRA1GABRB2FABP4FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030082101-A1 | Accelerators for increasing the rate of formation of free radicals and reactive oxygen species | CAVALIER DISCOVERY | 2003-05-01 | — | — | US | claimed |
| US-20030082101-A1 | Accelerators for increasing the rate of formation of free radicals and reactive oxygen species | CAVALIER DISCOVERY | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082101-A1 | Accelerators for increasing the rate of formation of free radicals and reactive oxygen species | SOD1, SOD3, APEX1 | ROCK2 2727/4885GABRA1 3872/4885GABRB2 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.