Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329823 | 0.85 | SRC (0.55) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL6553840 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL181586 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL29922833 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL6553836 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL4641676 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL4645166 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL3763474 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL15700118 | 0.77 | CA1 (0.41) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL4641996 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131018-A1 | SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS | EXONHIT S.A. (FR) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131018-A1 | SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS | TUBB3, TUBB, TUBB1 | ALDH1A1 2257/4885SMN1; SMN2 2218/4885HPGD 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.