Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035563 | 0.85 | FOLH1 (0.56) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL15142867 | 0.84 | FOLH1 (0.54) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL24835146 | 0.80 | ALDH1A1 (0.55) | ACHE | |
| SCHEMBL30354557 | 0.80 | FOLH1 (0.61) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL991080 | 0.80 | FOLH1 (0.61) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL371526 | 0.79 | FOLH1 (0.70) | FOLH1MRGPRX4MEP1AMEP1BCYP2D6 | |
| SCHEMBL27598641 | 0.79 | FOLH1 (0.49) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL27666658 | 0.78 | FOLH1 (0.51) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL40108 | 0.78 | MEP1B (0.51) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL4407864 | 0.77 | MEP1B (0.65) | FOLH1MRGPRX4TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |