Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778776 | 0.77 | PTGDR2 (0.42) | MAOAMAOBPTGDR2MEN1KMT2A | |
| SCHEMBL283161 | 0.77 | MAOA (0.55) | MAOAMAOBSOS1MEN1KMT2A | |
| SCHEMBL15904561 | 0.76 | HSD17B10 (0.45) | MAOAMAOBPTGDR2SOS1MEN1 | |
| SCHEMBL27521693 | 0.75 | MAOA (0.52) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL28014796 | 0.75 | NPBWR1 (0.42) | MAOAMAOBPTGDR2ALDH1A1CYP1A2 | |
| SCHEMBL282516 | 0.75 | SOS1 (0.45) | MAOAMAOBPTGDR2SOS1MEN1 | |
| SCHEMBL14959657 | 0.73 | PTGS2 (0.53) | SOS1SLC6A4PTGS1PTGS2 | |
| SCHEMBL282676 | 0.73 | HSPB1 (0.49) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL14997968 | 0.72 | NPBWR1 (0.44) | MAOAMAOBPTGDR2MEN1KMT2A | |
| SCHEMBL11989282 | 0.72 | PPARG (0.40) | MAOAMAOBPTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511488-B1 | HUMAN ADAM-10 INHIBITORS | SYMPHONY EVOLUTION INC (US) | 2013-05-22 | — | — | EP | disclosed |