Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401957 | 0.84 | CA12 (0.47) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4402097 | 0.82 | SMN1; SMN2 (0.49) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4399509 | 0.82 | NPC1 (0.54) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4403971 | 0.82 | ALDH1A1 (0.42) | HPGDALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL9086106 | 0.80 | GAA (0.44) | HPGDALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL22755094 | 0.80 | ALDH1A1 (0.40) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1205198 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2TSHRHTTMEN1 | |
| SCHEMBL12995665 | 0.78 | PSMB8 (0.46) | — | |
| SCHEMBL1162081 | 0.78 | MAPT (0.51) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15836548 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRHDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |