Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162081 | 0.83 | MAPT (0.51) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4401957 | 0.82 | CA12 (0.47) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL14960465 | 0.82 | HPGD (0.43) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL4402097 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4399509 | 0.81 | NPC1 (0.54) | ALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL9086106 | 0.79 | GAA (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22755094 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1205198 | 0.77 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL12995665 | 0.77 | PSMB8 (0.46) | — | |
| SCHEMBL23049302 | 0.76 | HTR7 (0.48) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120107942-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-8124792-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2012-02-28 | — | — | US | disclosed |