Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22295270 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL19386385 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL22755094 | 0.88 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL4401957 | 0.86 | CA12 (0.47) | ALDH1A1RAB9AHPGDPOLBKMT2A | |
| SCHEMBL9086106 | 0.83 | GAA (0.44) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL14960465 | 0.82 | HPGD (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL4399509 | 0.81 | NPC1 (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL4403971 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1NPC1L3MBTL1HPGD | |
| SCHEMBL1205198 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL27807368 | 0.79 | PARP10 (0.42) | ALDH1A1L3MBTL1HPGDPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4033223-B1 | METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME | WATERS TECHNOLOGIES CORP (US) | 2025-06-18 | — | — | EP | disclosed |
| US-12158472-B2 | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same | WATERS TECHNOLOGIES CORPORATION (US) | 2024-12-03 | — | — | US | disclosed |
| US-11747310-B2 | Methods for liquid chromatography calibration for rapid labeled N-glycans | WATERS TECHNOLOGIES CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| US-11747310-B2 | Methods for liquid chromatography calibration for rapid labeled N-glycans | WATERS TECHNOLOGIES CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| US-11747310-B2 | Methods for liquid chromatography calibration for rapid labeled N-glycans | WATERS TECHNOLOGIES CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| EP-3744708-B1 | CALIBRANT FOR LIQUID CHROMATOGRAPHY CALIBRATION OF LABELED N-GLYCANS | WATERS TECHNOLOGIES CORP (US) | 2023-08-09 | — | — | EP | disclosed |
| US-20220268779-A1 | METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME | WATERS TECHNOLOGIES CORPORATION (US) | 2022-08-25 | — | — | US | disclosed |
| EP-4033223-A1 | METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME | Waters Technologies Corporation (US) | 2022-07-27 | — | — | EP | disclosed |
| US-11371996-B2 | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same | WATERS TECHNOLOGIES CORPORATION (US) | 2022-06-28 | — | — | US | disclosed |
| US-11371996-B2 | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same | WATERS TECHNOLOGIES CORPORATION (US) | 2022-06-28 | — | — | US | disclosed |
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120107942-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-8124792-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2009100155-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| US-6218379-B1 | Tricyclic carbacephems | HOFFMANN-LA ROCHE INC. | 2001-04-17 | — | — | US | disclosed |
| EP-0912574-A1 | BETA-LACTAMS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997045429-A1 | BETA-LACTAMS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-12-04 | — | — | WO | disclosed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11747310-B2 | Methods for liquid chromatography calibration for rapid labeled N-glycans | DDOST, STT3B, CSGALNACT1 | SMN1; SMN2 4368/4885ALDH1A1 1045/4885MAPK1 1215/4885 |
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | B3GNT2, FUT5, FUT6 | SMN1; SMN2 4712/4885ALDH1A1 2931/4885MAPK1 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.