Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402097 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL1205198 | 0.85 | SMN1; SMN2 (0.51) | ALDH1A1MEN1KMT2AEPHX2LMNA | |
| SCHEMBL9086106 | 0.84 | GAA (0.44) | CA12CA1CA9ALDH1A1HPGD | |
| SCHEMBL14960465 | 0.84 | HPGD (0.43) | ALDH1A1HPGDMEN1KMT2AEPHX2 | |
| SCHEMBL22755094 | 0.84 | ALDH1A1 (0.40) | CA1CA9ALDH1A1HPGDMEN1 | |
| SCHEMBL4399509 | 0.83 | NPC1 (0.54) | ALDH1A1POLBLMNATDP1RAB9A | |
| SCHEMBL4403971 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL4401953 | 0.82 | MEN1 (0.48) | MITFALDH1A1MEN1KMT2ANR1H4 | |
| SCHEMBL10063822 | 0.81 | ALDH1A1 (0.48) | CA12CA1CA9MITFALDH1A1 | |
| SCHEMBL12995665 | 0.79 | PSMB8 (0.46) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12092644-B2 | Kits comprising aldehydes to reduce artifacts in analyzing glycans released from glycoproteins or glycopeptides | AGILENT TECHNOLOGIES, INC. (US) | 2024-09-17 | — | — | US | claimed |
| EP-3500842-B1 | USE OF MILD ELECTROPHILES TO REDUCE ARTIFACTS IN ANALYZING GLYCANS RELEASED FROM GLYCOPROTEINS OR GLYCOPEPTIDES | AGILENT TECHNOLOGIES INC (US) | 2024-04-10 | — | — | EP | claimed |
| CN-108884030-B | Improved labeling of nucleophiles using bipyridines | 安捷伦科技有限公司 | 2022-06-28 | — | — | CN | claimed |
| US-20210333269-A1 | Kits for Using Bispyridines to Improve Labeling of Nucleophiles | AGILENT TECHNOLOGIES, INC. (US) | 2021-10-28 | — | — | US | claimed |
| US-11035862-B2 | Use of mild electrophiles to reduce artifacts in analyzing glycans released from glycoproteins or glycopeptides | AGILENT TECHNOLOGIES, INC. (US) | 2021-06-15 | — | — | US | claimed |
| EP-3500842-A1 | USE OF MILD ELECTROPHILES TO REDUCE ARTIFACTS IN ANALYZING GLYCANS RELEASED FROM GLYCOPROTEINS OR GLYCOPEPTIDES | Prozyme, Inc. (US) | 2019-06-26 | — | — | EP | claimed |
| US-20190170763-A1 | USE OF MILD ELECTROPHILES TO REDUCE ARTIFACTS IN ANALYZING GLYCANS RELEASED FROM GLYCOPROTEINS OR GLYCOPEPTIDES | PROZYME, INC. (US) | 2019-06-06 | — | — | US | claimed |
| WO-2018035271-A1 | USE OF MILD ELECTROPHILES TO REDUCE ARTIFACTS IN ANALYZING GLYCANS RELEASED FROM GLYCOPROTEINS OR GLYCOPEPTIDES | PROZYME, INC. (US) | 2018-02-22 | — | — | WO | claimed |
| US-12092644-B2 | Kits comprising aldehydes to reduce artifacts in analyzing glycans released from glycoproteins or glycopeptides | AGILENT TECHNOLOGIES, INC. (US) | 2024-09-17 | — | — | US | disclosed |
| EP-3500842-B1 | USE OF MILD ELECTROPHILES TO REDUCE ARTIFACTS IN ANALYZING GLYCANS RELEASED FROM GLYCOPROTEINS OR GLYCOPEPTIDES | AGILENT TECHNOLOGIES INC (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-3419963-B1 | USE OF BISPYRIDINES TO IMPROVE LABELING OF NUCLEOPHILES | AGILENT TECHNOLOGIES INC (US) | 2022-08-10 | — | — | EP | disclosed |
| CN-108884030-B | Improved labeling of nucleophiles using bipyridines | 安捷伦科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-20210333269-A1 | Kits for Using Bispyridines to Improve Labeling of Nucleophiles | AGILENT TECHNOLOGIES, INC. (US) | 2021-10-28 | — | — | US | disclosed |
| US-11092595-B2 | Use of bispyridines to improve labeling of nucleophiles | AGILENT TECHNOLOGIES, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20120107942-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-8124792-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124792-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2009100155-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11092595-B2 | Use of bispyridines to improve labeling of nucleophiles | PTMS, BTD, DPYD | CA12 3801/4885CA1 3538/4885CA9 3871/4885 |
| US-20210333269-A1 | Kits for Using Bispyridines to Improve Labeling of Nucleophiles | DPYD, UNG, BTD | CA12 3735/4885CA1 3292/4885CA9 2765/4885 |
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | B3GNT2, FUT5, FUT6 | CA12 75/4885CA1 307/4885CA9 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.