Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180160 | 0.84 | LMNA (0.54) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| SCHEMBL10024370 | 0.84 | LMNA (0.54) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| SCHEMBL7525226 | 0.84 | LMNA (0.54) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| Acetic Acid SCHEMBL8192834 | 0.82 | ALOX5 (0.46) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| SCHEMBL8178447 | 0.81 | ALOX5 (0.48) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| SCHEMBL25896589 | 0.80 | LMNA (0.50) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| SCHEMBL25896595 | 0.80 | LMNA (0.50) | HPGDLMNAMAPK1ADRA2CKDM4E | |
| SCHEMBL107151 | 0.80 | HPGD (0.48) | HPGDLMNAMAPK1ADRA2CADRA2A | |
| SCHEMBL4568744 | 0.80 | CYP3A4 (0.49) | HPGDLMNAMAPK1CYP2D6SRC | |
| SCHEMBL15342224 | 0.80 | CYP3A4 (0.49) | HPGDLMNAMAPK1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206405-B2 | Glycosyl hydrolase with beta-xylosidase and beta-glucosidase activities and uses thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2015-12-08 | — | — | US | disclosed |
| US-20130130330-A1 | NOVEL GLYCOSYL HYDROLASE WITH BETA-XYLOSIDASE AND BETA-GLUCOSIDASE ACTIVITIES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF ME SCIENCES (CN) | 2013-05-23 | — | — | US | disclosed |