SCHEMBL14962008

SCHEMBL14962008

CC(C)(C)c1cc2cc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)o3)c3cc(C(C)(C)C)cc4cc(-c5ccc(N(c6ccccc6)c6cccc7ccccc67)o5)c(c1)c2c43

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.33
NR1I2 O75469 1/20 0.31
LMNA P02545 1/20 0.31
ADRA2A P08913 1/20 0.31
CYP2D6 P10635 1/20 0.31
ACHE P22303 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
SLC6A4 P31645 1/20 0.31
KCNH2 Q12809 1/20 0.31
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962006 0.89 CYP2D6 (0.32) LMNACYP2D6GPR84
SCHEMBL14962003 0.88
SCHEMBL14962009 0.88 SIGMAR1 (0.30) SIGMAR1
SCHEMBL14962002 0.85 SIGMAR1 (0.36) SIGMAR1ACHE
SCHEMBL14962005 0.78 ADORA3 (0.36) SIGMAR1
SCHEMBL14962010 0.76
SCHEMBL14961999 0.76 ALDH1A1 (0.34) ACHE
SCHEMBL14962015 0.76
SCHEMBL8204842 0.74 SIGMAR1 (0.44) SIGMAR1CYP2D6SLC6A2SLC6A4
SCHEMBL12700269 0.72 SIGMAR1 (0.40) SIGMAR1NR1I2LMNAADRA2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element UDC IRELAND LIMITED (IE) 2023-01-24 US disclosed
US-20180069179-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LTD (IE) 2018-03-08 US disclosed
US-20180069179-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LTD (IE) 2018-03-08 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180069179-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 SIGMAR1 1001/4885NR1I2 557/4885LMNA 3527/4885
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element L1CAM, RER1, H1-0 SIGMAR1 1001/4885NR1I2 557/4885LMNA 3527/4885
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 SIGMAR1 1001/4885NR1I2 557/4885LMNA 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.