SCHEMBL1496282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496366	0.87	KDR (0.66)	KDRFLT1MEN1KMT2AOPRL1
	SCHEMBL1496283	0.87	ACLY (0.50)	KDRFLT1OPRL1NPC1LMNA
	SCHEMBL1496358	0.86	KDR (0.59)	KDRFLT1MEN1KMT2ALMNA
	SCHEMBL1496374	0.85	KDR (0.59)	KDRFLT1
	SCHEMBL1496259	0.85	KDR (0.58)	KDRMEN1KMT2AOPRL1NPC1
	SCHEMBL1496331	0.84	PKM (0.56)	KDRMEN1KMT2ALMNAPOLB
	SCHEMBL1496324	0.83	KDR (0.63)	KDRFLT1KMT2AOPRL1IDO1
	SCHEMBL4977752	0.79	KDR (0.55)	KDRFLT1MEN1KMT2AOPRL1
	SCHEMBL1347578	0.79	KDR (0.55)	KDRFLT1MEN1KMT2AOPRL1
	SCHEMBL1496378	0.79	SMN1; SMN2 (0.44)	KDRFLT1KMT2ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.