SCHEMBL149648

SCHEMBL149648

NC(=O)c1cn([C@H]2C[C@H](O)[C@@H](CO)O2)cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.50
DNMT1 P26358 1/20 0.50
PIM1 P11309 1/20 0.44
CSNK2A2 P19784 1/20 0.44
CSNK2B P67870 1/20 0.44
CSNK2A1 P68400 1/20 0.44
CSNK2A3 Q8NEV1 1/20 0.44
LMNA P02545 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
PNP P00491 1/20 0.43
TP53 P04637 1/20 0.43
HTT P42858 1/20 0.43
PDE4D Q08499 1/20 0.43
PDE3A Q14432 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
TK1 P04183 1/20 0.42
HIF1A Q16665 1/20 0.41
ADA P00813 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2193016 1.00 ADRB1 (0.50) ADRB1DNMT1PIM1CSNK2A2CSNK2B
SCHEMBL21887947 0.83 TYMS (0.47)
SCHEMBL11386837 0.81 ADRB1 (0.54) ADRB1DNMT1PIM1CSNK2A2CSNK2B
SCHEMBL8625601 0.80 LMNA (0.46) ADRB1DNMT1PIM1CSNK2A2CSNK2B
SCHEMBL4078996 0.76 ALDH1A1 (0.42) LMNASMN1; SMN2HTTADAADORA1
SCHEMBL7213155 0.76 LMNA (0.57) DNMT1LMNASMN1; SMN2PNPTP53
SCHEMBL2481555 0.76 LMNA (0.57) DNMT1LMNASMN1; SMN2PNPTP53
SCHEMBL4074386 0.76 ALDH1A1 (0.42) LMNASMN1; SMN2HTTADAADORA1
SCHEMBL12669988 0.76 LMNA (0.57) DNMT1LMNASMN1; SMN2PNPTP53
SCHEMBL8722885 0.76 LMNA (0.57) DNMT1LMNASMN1; SMN2PNPTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2322649-B1 Method for rapid detection and identification of bioagents IBIS BIOSCIENCES INC (US) 2013-12-18 EP claimed
EP-1364064-B1 METHOD FOR RAPID DETECTION AND IDENTIFICATION OF BACTERIA IBIS BIOSCIENCES INC (US) 2012-08-01 EP claimed
EP-2322649-A1 Method for rapid detection and identification of bioagents Ibis Biosciences, Inc. (US) 2011-05-18 EP claimed
EP-1364064-A4 METHOD FOR RAPID DETECTION AND IDENTIFICATION OF BIOAGENTS ISIS PHARMACEUTICALS INC (US) 2005-11-23 EP claimed
US-20050123952-A1 Methods of rapid detection and identification of bioagents using microRNA ISIS PHARMACEUTICALS, INC. 2005-06-09 US claimed
WO-2005033271-A2 METHODS OF RAPID DETECTION AND IDENTIFICATION OF BIOAGENTS USING microRNA ISIS PHARMACEUTICALS, INC. (US) 2005-04-14 WO claimed
WO-2005024046-A2 METHODS OF DETECTION AND NOTIFICATION OF BIOAGENT CONTAMINATION ISIS PHARMACEUTICALS, INC. (US) 2005-03-17 WO claimed
US-20040253583-A1 By a combination of nucleic acid amplification (PCR, ligase chain reaction, and/or strand displacement amplification) and molecular weight determination using primers which hybridize to conserved sequence regions of nucleic acids derived from bioagent, and forming profile on database IBIS BIOSCIENCES, INC. 2004-12-16 US claimed
US-20040253619-A1 Methods for rapid detection and identification of bacterial bioagents IBIS BIOSCIENCES, INC. 2004-12-16 US claimed
US-20040202997-A1 Method for rapid detection and identification of bioagents IBIS BIOSCIENCES, INC. 2004-10-14 US claimed
US-20030228571-A1 Method for rapid detection and identification of viral bioagents IBIS BIOSCIENCES, INC. 2003-12-11 US claimed
WO-2003100035-A2 METHOD FOR RAPID DETECTION AND IDENTIFICATION OF VIRAL BIOAGENTS ISIS PHARMACEUTICALS, INC. (US) 2003-12-04 WO claimed
EP-1364064-A2 METHOD FOR RAPID DETECTION AND IDENTIFICATION OF BIOAGENTS ISIS PHARMACEUTICALS, INC. (US) 2003-11-26 EP claimed
US-20030190605-A1 Methods for rapid detection and identification of bioagents for environmental testing IBIS BIOSCIENCES, INC. 2003-10-09 US claimed
US-20030175697-A1 Comprises primers which hybridize conserved sequences; polymerase chain reactions; ribonucleases; mass spectrometry; drug screening IBIS BIOSCIENCES, INC. 2003-09-18 US claimed
US-20030175696-A1 Method for rapid detection and identification of bioagents IBIS BIOSCIENCES, INC. 2003-09-18 US claimed
US-20030175695-A1 Method for rapid detection and identification of bioagents IBIS BIOSCIENCES, INC. 2003-09-18 US claimed
US-20030124556-A1 Method for rapid detection and identification of bioagents IBIS BIOSCIENCES, INC. 2003-07-03 US claimed
US-20030027135-A1 Method for rapid detection and identification of bioagents IBIS BIOSCIENCES, INC. 2003-02-06 US claimed
WO-2002070664-A2 METHOD FOR RAPID DETECTION AND IDENTIFICATION OF BIOAGENTS ISIS PHARMACEUTICALS, INC. (US) 2002-09-12 WO claimed