Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929690 | 0.90 | LMNA (0.41) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL7928080 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL2193016 | 0.80 | ADRB1 (0.50) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL149648 | 0.80 | ADRB1 (0.50) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL5983012 | 0.77 | TK1 (0.69) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL5983020 | 0.77 | TK1 (0.69) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL15285228 | 0.77 | TK1 (0.69) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL5983240 | 0.76 | DNMT1 (0.61) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL27093305 | 0.76 | DNMT1 (0.61) | LMNASMN1; SMN2TK1ADRB1DNMT1 | |
| SCHEMBL5983245 | 0.76 | DNMT1 (0.61) | LMNASMN1; SMN2TK1ADRB1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885235-A1 | NUCLEOSIDE ANALOGUES | Amersham Pharmacia Biotech UK Limited (GB) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997028176-A1 | NUCLEOSIDE ANALOGUES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |