SCHEMBL149649

SCHEMBL149649

N#Cc1c(F)c(F)[c]c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17835439 0.89 TRPV4 (0.31) TRPV4
SCHEMBL9116984 0.85
SCHEMBL2316921 0.83 TRPV4 (0.31) TRPV4
SCHEMBL17023417 0.79
SCHEMBL57543 0.77 TRPV4 (0.41) TRPV4
SCHEMBL9625848 0.77 TRPV4 (0.41) TRPV4
SCHEMBL9116470 0.74 TRPV4 (0.32) TRPV4
SCHEMBL31612588 0.74 TRPV4 (0.39) TRPV4
Ammonia Solution, Strong SCHEMBL27947136 0.74 TRPV4 (0.39) TRPV4
SCHEMBL250738 0.74 TRPV4 (0.39) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140294-A1 ORGANIC COMPOUND AND APPLICATION THEREOF IN OLED DEVICE 北京云基科技股份有限公司 2024-07-04 WO claimed
US-11950507-B2 Organic electroluminescence device Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-04-02 US claimed
CN-114335361-B Composition and organic electroluminescent device comprising same 江苏三月科技股份有限公司 2024-03-22 CN claimed
CN-114335364-B Composition for organic electroluminescent device and organic electroluminescent device 江苏三月科技股份有限公司 2024-03-22 CN claimed
CN-117693217-A Series organic electroluminescent device 北京夏禾科技有限公司 2024-03-12 CN claimed
CN-114516821-B Compound containing multiple rings, application and organic electroluminescent device 宁波卢米蓝新材料有限公司 2024-02-13 CN claimed
US-11897896-B2 Organic electroluminescent materials and devices Beijing Summer Sprout Technology Co., Ltd. 2024-02-13 US claimed
CN-114335362-B OLED (organic light emitting diode) composition and organic electroluminescent device 江苏三月科技股份有限公司 2024-02-13 CN claimed
CN-114573481-B Compound containing multiple rings, application and organic electroluminescent device 宁波卢米蓝新材料有限公司 2024-02-09 CN claimed
CN-114335363-B Composition for organic electroluminescent device and organic electroluminescent device 江苏三月科技股份有限公司 2024-01-30 CN claimed
US-20030114696-A1 Phosphinimine methanide transition metal catalysts THE GOVERNORS OF THE UNIVERSITY OF ALBERTA 2003-06-19 US claimed
US-6538115-B2 Basic structure N=P-C(=M)-P=N where P is phosphorus, N is nitrogen, M is a transition or lanthanide metal and P,M and N atoms are substituted; making complex by reacting the corresponding diilithium salt with a metal compound THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2003-03-25 US claimed
US-6500842-B1 N-((4-CHLOROPHENYL)METHYL)-8-HYDROXY-7-QUINOLINECARBOXAMIDE ADMINISTERED AS VIRICIDES AGAINST HERPES VIRUS PHARMACIA & UPJOHN COMPANY 2002-12-31 US claimed
US-20020161205-A1 Phosphorus supported carbene transition metal complexes THE GOVERNORS OF THE UNIVERSITY OF ALBERTA 2002-10-31 US claimed
US-6313331-B1 Carbene transition metal catalysts THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2001-11-06 US claimed
US-6310211-B1 ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 PHARMACIA & UPJOHN COMPANY 2001-10-30 US claimed
US-6252080-B1 HERPES, CYTOMEGALO VIRUS PHARMACIA & UPJOHN COMPANY 2001-06-26 US claimed
US-6060568-A Carbene transition metal catalysts THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2000-05-09 US claimed
EP-0927164-A1 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1999-07-07 EP claimed
WO-1998011073-A1 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1998-03-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897896-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, SLCO4C1 TRPV4 27/4885
US-20020161205-A1 Phosphorus supported carbene transition metal complexes PLTP, PLCG2, PLCB3 TRPV4 582/4885
US-20030114696-A1 Phosphinimine methanide transition metal catalysts TIMM9, TIMM13, TIMM10 TRPV4 927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.