SCHEMBL57543

SCHEMBL57543

N#Cc1c(F)c(F)c(C#N)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.41
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27947136 0.96 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL31612588 0.96 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL250738 0.96 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL809254 0.93 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL22322143 0.93 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL4094768 0.93 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL9625848 0.92 TRPV4 (0.41) TRPV4MEN1ALDH1A1TP53CYP3A4
Methyl Alcohol SCHEMBL2775838 0.89 TRPV4 (0.36) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL6049158 0.89 TRPV4 (0.36) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL30542039 0.88 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2147 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060158-A Solid electrolyte material based on in-situ integrated polyarylether covalent organic framework and preparation method thereof 石河子大学 2026-05-19 CN claimed
CN-122036554-A Fluorescent material based on chiral binaphthol and preparation method and application thereof 曲阜师范大学 2026-05-15 CN claimed
US-20260094872-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES SEPION TECH INC (US) 2026-04-02 US claimed
EP-4713026-A1 LONG-ACTING PAIN-RELIEF FORMULATION Centre National de la Recherche Scientifique (FR) 2026-03-25 EP claimed
US-12580201-B2 Electrode having high oxygen permeability for fuel cell and membrane-electrode assembly comprising same HYUNDAI MOTOR COMPANY (KR) 2026-03-17 US claimed
EP-4595143-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES Sepion Technologies, Inc. (US) 2025-08-06 EP claimed
CN-120202571-A Ternary solvent electrolyte for high voltage and high rate lithium battery 赛鹏科技有限公司 2025-06-24 CN claimed
EP-4569559-A1 GLASSY ORGANIC FRAMEWORK ION-CONDUCTIVE MEMBRANES Wisconsin Alumni Research Foundation (US) 2025-06-18 EP claimed
CN-120155071-A Self-polymerization microporous polymer hollow fiber ultrafiltration membrane and preparation method and application thereof 北京诺滤新材料科技有限公司 2025-06-17 CN claimed
CN-120149497-A Electrochemical device and electronic apparatus 深圳市豪鹏科技股份有限公司 2025-06-13 CN claimed
WO-2002028822-A2 PROCESS FOR PRODUCING FLUORINATED DICYANOBENZENE SHOWA DENKO K.K. (JP) 2002-04-11 WO claimed
WO-2002002504-A1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND SHOWA DENKO K.K. (JP) 2002-01-10 WO claimed
US-6020517-A Process for production of benzonitrile and benzyl alcohol SHOWA DENKO K.K. (JP) 2000-02-01 US claimed
US-5591378-A IN COMBINATION WITH PEROXYGEN SOURCE, FORMATION OF PEROXYIMIDIC ACID THE CLOROX COMPANY (US) 1997-01-07 US claimed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US claimed
EP-0099622-B1 PROCESS FOR THE HYDROGENATION OF PERHALOGENATED TEREPHTHALONITRILES TO AMINES, 2,3,5,6-TETRAFLUOROXYLYLENE DIAMINE AND SALTS THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-04 EP claimed
US-4556426-A HALOGENATED AROMATIC DINITRILES TILE COUNCIL OF AMERICA, INC. (US) 1985-12-03 US claimed
EP-0119701-A1 Grignard syntheses IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-09-26 EP claimed
EP-0099622-A1 Process for the hydrogenation of perhalogenated terephthalonitriles to amines, 2,3,5,6-tetrafluoroxylylene diamine and salts thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-02-01 EP claimed
US-3975424-A FROM TETRACHLOROPHTHALONITRILE AND POTASSIUM FLUORIDE AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) 1976-08-17 US claimed