Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27947136

N.N#Cc1c(F)c(F)c(C#N)c(F)c1F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.39
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57543 0.96 TRPV4 (0.41) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL31612588 0.92 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL250738 0.92 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL4094768 0.89 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL22322143 0.89 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL809254 0.89 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL9625848 0.88 TRPV4 (0.41) TRPV4MEN1ALDH1A1TP53CYP3A4
Methyl Alcohol SCHEMBL2775838 0.86 TRPV4 (0.36) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL6049158 0.86 TRPV4 (0.36) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL30542039 0.85 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103483199-B Preparation method of tetrafluoroterephthalate ZHEJIANG CHEMSYN PHARM CO LTD 2015-06-17 CN disclosed
CN-103483199-A Preparation method of tetrafluoroterephthalate ZHEJIANG CHEMSYN PHARM CO LTD 2014-01-01 CN disclosed