Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964862 | 0.95 | PTK2 (0.52) | PTK2 | |
| SCHEMBL14964952 | 0.90 | PTK2 (0.46) | PTK2 | |
| SCHEMBL14964954 | 0.89 | PTK2 (0.34) | PTK2 | |
| SCHEMBL14965320 | 0.89 | PTK2 (0.45) | PTK2 | |
| SCHEMBL14965062 | 0.85 | PTK2 (0.40) | PTK2 | |
| SCHEMBL14965152 | 0.78 | ADORA1 (0.37) | — | |
| SCHEMBL14965003 | 0.78 | ADORA3 (0.37) | — | |
| SCHEMBL14965011 | 0.77 | PTK2 (0.45) | PTK2 | |
| SCHEMBL14965112 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL14965341 | 0.76 | ADORA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |