Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965003 | 0.90 | ADORA3 (0.37) | ADORA1ADORA3ADORA2A | |
| SCHEMBL14965112 | 0.88 | ALDH1A1 (0.38) | — | |
| SCHEMBL14965152 | 0.86 | ADORA1 (0.37) | ADORA1ADORA3ADORA2A | |
| SCHEMBL14965245 | 0.79 | LMNA (0.49) | — | |
| SCHEMBL14964954 | 0.79 | PTK2 (0.34) | — | |
| SCHEMBL14964851 | 0.78 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL14965271 | 0.76 | PTK2 (0.47) | — | |
| SCHEMBL14965320 | 0.76 | PTK2 (0.45) | — | |
| SCHEMBL14965062 | 0.76 | PTK2 (0.40) | — | |
| SCHEMBL14964875 | 0.76 | SMN1; SMN2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |