Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 5/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031948 | 0.96 | ALOX15 (0.41) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8412132 | 0.92 | ALOX15 (0.42) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL26035581 | 0.90 | ALOX15 (0.33) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL4335588 | 0.90 | HIF1A (0.35) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL19952793 | 0.89 | TDP1 (0.45) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL19458 | 0.87 | TDP1 (0.42) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL16298510 | 0.87 | CHRM5 (0.38) | ALOX15KDM4EMAPTSMN1; SMN2TSHR | |
| SCHEMBL15548847 | 0.85 | NR1D1 (0.36) | TDP1CYP2D6NR1D1NR1H3CA14 | |
| SCHEMBL6273735 | 0.84 | GSTO1 (0.32) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL27420033 | 0.84 | NR1D1 (0.38) | TDP1CYP2D6NR1D1NR1H3CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230124554-A1 | FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS | UNIVERSITY OF WASHINGTON (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2023018816-A2 | ULTRALOW-FOULING ZWITTERIONIC POLYURETHANE-MODIFIED MEMBRANE METHODS AND DEVICES FOR RAPID SEPARATION OF PLASMA FROM WHOLE BLOOD | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-02-16 | — | — | WO | disclosed |
| US-20210163657-A1 | ZWITTERIONIC POLYMERS FOR BIOMEDICAL APPLICATIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2021-06-03 | — | — | US | disclosed |
| WO-2019204712-A1 | ZWITTERIONIC POLYMERS FOR BIOMEDICAL APPLICATIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-10-24 | — | — | WO | disclosed |
| EP-2482855-B1 | OLIGOMER-CALCIMIMETIC CONJUGATES AND RELATED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2017-12-27 | — | — | EP | disclosed |
| WO-2017003639-A2 | FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS | UNIVERSITY OF WASHINGTON (US) | 2017-01-05 | — | — | WO | disclosed |
| US-9421275-B2 | Oligomer-calcimimetic conjugates and related compunds | NEKTAR THERAPEUTICS (US) | 2016-08-23 | — | — | US | disclosed |
| US-9421275-B2 | Oligomer-calcimimetic conjugates and related compunds | NEKTAR THERAPEUTICS (US) | 2016-08-23 | — | — | US | disclosed |
| US-9421275-B2 | Oligomer-calcimimetic conjugates and related compunds | NEKTAR THERAPEUTICS (US) | 2016-08-23 | — | — | US | disclosed |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | NEKTAR THERAPEUTICS (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | NEKTAR THERAPEUTICS (US) | 2014-10-30 | — | — | US | disclosed |
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | NEKTAR THERAPEUTICS (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | NEKTAR THERAPEUTICS (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | NEKTAR THERAPEUTICS (US) | 2012-09-20 | — | — | US | disclosed |
| EP-2482855-A2 | OLIGOMER-CALCIMIMETIC CONJUGATES AND RELATED COMPOUNDS | Nektar Therapeutics (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011056325-A2 | OLIGOMER-CALCIMIMETIC CONJUGATES AND RELATED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20080305070-A1 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON PHARMACEUTICALS, INC. (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | CALCR, CALCB, CALCA | ALOX15 3059/4885KDM4E 4830/4885MAPT 842/4885 |
| US-20230124554-A1 | FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS | FGB, FN1, MSN | ALOX15 1231/4885KDM4E 4442/4885MAPT 1575/4885 |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | CALCR, CALCB, CALCA | ALOX15 3580/4885KDM4E 4843/4885MAPT 847/4885 |
| US-20080305070-A1 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | CD44, PAICS, PCBP1 | ALOX15 1113/4885KDM4E 2733/4885MAPT 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.