Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965986 | 0.88 | KCNJ1 (0.41) | CYP11B1KCNH2KCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL14966215 | 0.87 | CYP11B1 (0.43) | CAMKK2SRCCYP11B1KCNH2KCNJ1 | |
| SCHEMBL14966317 | 0.86 | LOXL2 (0.42) | TGFBR1HTR1ADRD2SMN1; SMN2MAPKAPK2 | |
| SCHEMBL14966162 | 0.86 | CHRM1 (0.36) | KCNH2TGFBR1HTR1ADRD2SMN1; SMN2 | |
| SCHEMBL14965795 | 0.86 | CYP11B1 (0.45) | SRCCYP11B1KCNH2KCNJ1HTR1A | |
| SCHEMBL14965790 | 0.84 | DRD2 (0.38) | SRCCYP11B1KCNH2KCNJ1HTR1A | |
| SCHEMBL14965683 | 0.83 | DRD2 (0.43) | KCNH2HTR1ADRD2 | |
| SCHEMBL14965893 | 0.83 | SCN9A (0.37) | SRCCYP11B1KCNH2KCNJ1HTR1A | |
| SCHEMBL14965635 | 0.82 | ALDH1A1 (0.42) | KCNH2KCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL14966336 | 0.82 | DRD2 (0.45) | CYP11B1KCNH2KCNJ1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |