Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965443 | 0.90 | — | — | |
| SCHEMBL14965126 | 0.88 | ADRB2 (0.60) | ADRB2ADRB3ADRB1 | |
| SCHEMBL16293296 | 0.81 | POLB (0.62) | — | |
| SCHEMBL14964774 | 0.79 | POLB (0.66) | — | |
| SCHEMBL16293411 | 0.77 | POLB (0.56) | — | |
| SCHEMBL14965005 | 0.77 | LMNA (0.64) | — | |
| SCHEMBL14965176 | 0.76 | POLB (0.60) | — | |
| SCHEMBL14965361 | 0.76 | POLB (0.62) | — | |
| SCHEMBL16293150 | 0.75 | POLB (0.61) | — | |
| SCHEMBL14965145 | 0.75 | POLB (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |