Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046316 | 0.81 | CHRM1 (0.40) | CHRM1KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL14966101 | 0.81 | CHRM1 (0.35) | CHRM1KCNH2ALDH1A1 | |
| SCHEMBL14965582 | 0.81 | HSD17B10 (0.38) | CHRM1KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL14965986 | 0.79 | KCNJ1 (0.41) | CHRM1KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL14965773 | 0.79 | L3MBTL1 (0.46) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL14965810 | 0.78 | KCNH2 (0.35) | CHRM1KCNH2ALDH1A1 | |
| SCHEMBL14965891 | 0.78 | CHRM1 (0.36) | CHRM1KCNH2ALDH1A1MAPT | |
| SCHEMBL14965791 | 0.77 | KDM4E (0.36) | CHRM1KCNH2ALDH1A1LMNA | |
| SCHEMBL14965999 | 0.77 | ALDH1A1 (0.43) | CHRM1ALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL14966005 | 0.77 | PKM (0.45) | ALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |