Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965938 | 0.86 | CHRM1 (0.34) | CHRM1KCNH2MEN1KMT2A | |
| SCHEMBL14965376 | 0.81 | CHRM1 (0.35) | CHRM1KCNH2 | |
| SCHEMBL14966094 | 0.81 | PDE7A (0.33) | CHRM1 | |
| SCHEMBL14965864 | 0.81 | ITGB3 (0.39) | CHRM1KCNH2KMT2A | |
| SCHEMBL14965567 | 0.80 | CHRM1 (0.36) | CHRM1KCNH2 | |
| SCHEMBL14965829 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL1046316 | 0.79 | CHRM1 (0.40) | CHRM1KCNH2KMT2A | |
| Hydrochloric Acid SCHEMBL14965816 | 0.79 | CHRM1 (0.36) | CHRM1KCNH2 | |
| SCHEMBL14971162 | 0.77 | DRD2 (0.38) | CHRM1 | |
| SCHEMBL14965372 | 0.75 | KCNH2 (0.38) | CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |