Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966116 | 0.86 | MAPT (0.46) | ALDH1A1KMT2AMEN1LMNAGPR174 | |
| SCHEMBL14965900 | 0.81 | GPR183 (0.41) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL14966119 | 0.81 | KMT2A (0.52) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL14966005 | 0.81 | PKM (0.45) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL1046316 | 0.80 | CHRM1 (0.40) | ALDH1A1KMT2ALMNAMAPTPKM | |
| SCHEMBL14965559 | 0.79 | KMT2A (0.42) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL14965372 | 0.78 | KCNH2 (0.38) | ALDH1A1LMNAMAPTPKMKCNH2 | |
| SCHEMBL14966340 | 0.78 | KMT2A (0.46) | ALDH1A1KMT2ALMNA | |
| SCHEMBL14965651 | 0.77 | HPGD (0.43) | ALDH1A1KMT2ALMNAGAAMAPT | |
| SCHEMBL14965726 | 0.77 | NPC1 (0.45) | ALDH1A1KMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |