Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965651 | 0.83 | HPGD (0.43) | GPR183KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL14965869 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14965999 | 0.80 | ALDH1A1 (0.43) | GPR183ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL14965706 | 0.78 | MEN1 (0.45) | GPR183KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14965625 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2L3MBTL1MAPTLMNA | |
| SCHEMBL14965565 | 0.77 | KMT2A (0.43) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14965860 | 0.76 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14966119 | 0.76 | KMT2A (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14966116 | 0.75 | MAPT (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14966218 | 0.74 | KMT2A (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |