Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966188 | 0.97 | KDM4E (0.50) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14966181 | 0.96 | KDM4E (0.56) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14965672 | 0.89 | DRD4 (0.47) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14965796 | 0.88 | MCHR1 (0.45) | KDM4EKMT2AMCHR1ALDH1A1MEN1 | |
| SCHEMBL14965370 | 0.86 | ALDH1A1 (0.44) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14965407 | 0.86 | KCNJ1 (0.42) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14969456 | 0.85 | POLB (0.43) | KDM4EKMT2ASMN1; SMN2MCHR1ALDH1A1 | |
| SCHEMBL14965822 | 0.85 | FGFR1 (0.45) | KDM4EDRD4MCHR1FGFR1FGFR2 | |
| SCHEMBL14965322 | 0.85 | KMT2A (0.45) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14965777 | 0.85 | HIF1A (0.58) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |