Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965840 | 0.91 | HRH3 (0.57) | HRH3SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14965690 | 0.88 | HRH3 (0.54) | HRH3SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14966002 | 0.88 | HPGD (0.54) | HRH3SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14965793 | 0.87 | HPGD (0.53) | HRH3SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14965949 | 0.85 | HPGD (0.51) | HRH3SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14965948 | 0.84 | HPGD (0.50) | HRH3SMN1; SMN2ALDH1A1PKMNPSR1 | |
| SCHEMBL14965407 | 0.82 | KCNJ1 (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2APKM | |
| SCHEMBL14969456 | 0.82 | POLB (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14965370 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL14965684 | 0.81 | CHKA (0.45) | HRH3SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |