Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965690 | 0.92 | HRH3 (0.54) | CHKAL3MBTL1HRH3BLMMEN1 | |
| SCHEMBL14965840 | 0.89 | HRH3 (0.57) | CHKAL3MBTL1HRH3BLMMEN1 | |
| SCHEMBL14965626 | 0.88 | LTA4H (0.40) | L3MBTL1SLC2A1SUCNR1FAAHMEN1 | |
| SCHEMBL14965511 | 0.88 | LTA4H (0.40) | L3MBTL1SLC2A1SUCNR1FAAHMEN1 | |
| SCHEMBL14965877 | 0.87 | MET (0.42) | CHKAHRH3SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14966243 | 0.86 | TNIK (0.45) | L3MBTL1ERN1SUCNR1FAAHMGLL | |
| SCHEMBL14965896 | 0.85 | SUCNR1 (0.40) | SLC2A1SUCNR1MEN1KMT2ALMNA | |
| SCHEMBL14971109 | 0.85 | TP53 (0.40) | SLC2A1SMN1; SMN2LMNATSHRMAPK1 | |
| SCHEMBL14969471 | 0.84 | KDM4E (0.41) | ERN1SUCNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14965949 | 0.84 | HPGD (0.51) | CHKAHRH3MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |