Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966156 | 0.91 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL14969412 | 0.91 | NR1D1 (0.36) | KCNH2MITFSOS1ALDH1A1OPRM1 | |
| SCHEMBL14965763 | 0.90 | MITF (0.34) | KCNH2MITFSOS1TRPA1OPRM1 | |
| SCHEMBL14969684 | 0.90 | NR1D1 (0.36) | MITFSOS1ALDH1A1 | |
| SCHEMBL14965901 | 0.88 | MITF (0.37) | MITFSOS1ALDH1A1 | |
| SCHEMBL14965539 | 0.83 | NR1H3 (0.39) | MITFALDH1A1 | |
| SCHEMBL14971142 | 0.83 | KCNH2 (0.39) | KCNH2CHRM1MITFSLC6A4PTGS1 | |
| SCHEMBL14965734 | 0.82 | NR1D1 (0.38) | MITFALDH1A1 | |
| SCHEMBL14965947 | 0.82 | MEP1B (0.37) | KCNH2MITF | |
| SCHEMBL14965850 | 0.80 | MITF (0.35) | MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |