SCHEMBL14966595

SCHEMBL14966595

CC(C)(C)OC(=O)C1(c2ccccc2)OC12CCCC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.39
APOBEC3A P31941 3/20 0.36
APOBEC3G Q9HC16 3/20 0.36
PRCP P42785 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
HDAC4 P56524 2/20 0.36
ALDH1A1 P00352 3/20 0.35
POLB P06746 1/20 0.35
CHRM3 P20309 1/20 0.35
TSHR P16473 3/20 0.35
ALOX15 P16050 1/20 0.35
ATM Q13315 1/20 0.35
HTT P42858 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967469 0.99 AKR1C1 (0.38) AKR1C1APOBEC3AAPOBEC3GPRCPSIGMAR1
SCHEMBL14967774 0.97 SMN1; SMN2 (0.36) AKR1C1APOBEC3AAPOBEC3GPRCPSIGMAR1
SCHEMBL14968351 0.87 MAPT (0.36) ALDH1A1POLBKDM4ELMNACYP3A4
SCHEMBL14967944 0.86 MAPT (0.36) ALDH1A1POLBKDM4ELMNACYP3A4
SCHEMBL14967508 0.85 CYP3A4 (0.41) ALDH1A1POLBKDM4ELMNACYP3A4
SCHEMBL14967473 0.84 OPRM1 (0.34) ALDH1A1POLBKDM4ELMNACYP3A4
SCHEMBL14968200 0.84 SLC6A4 (0.42) ALDH1A1KDM4ELMNACYP3A4TDP1
SCHEMBL14968268 0.84 MEN1 (0.46) AKR1C1APOBEC3AAPOBEC3GPRCPSIGMAR1
SCHEMBL14967505 0.82 MEN1 (0.45) AKR1C1APOBEC3AAPOBEC3GHDAC4ALDH1A1
SCHEMBL14967934 0.82 CYP3A4 (0.39) ALDH1A1POLBATMKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed