SCHEMBL14967774

SCHEMBL14967774

CC(C)(C)OC(=O)C1(c2ccccc2)OC12CCC2

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
AKR1C1 Q04828 1/20 0.36
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
ATM Q13315 1/20 0.35
APOBEC3A P31941 2/20 0.34
APOBEC3G Q9HC16 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
RORC P51449 5/20 0.33
OPRM1 P35372 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PRCP P42785 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
TACR1 P25103 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966595 0.97 AKR1C1 (0.39) AKR1C1TSHRALOX15ATMAPOBEC3A
SCHEMBL14967469 0.96 AKR1C1 (0.38) SMN1; SMN2AKR1C1APOBEC3AAPOBEC3GMEN1
SCHEMBL14967473 0.87 OPRM1 (0.34) SMN1; SMN2KMT2AOPRM1ALDH1A1
SCHEMBL14967934 0.85 CYP3A4 (0.39) SMN1; SMN2ATMALDH1A1
SCHEMBL14968351 0.84 MAPT (0.36) SMN1; SMN2KMT2AOPRM1ALDH1A1
SCHEMBL14968183 0.84 MEN1 (0.46) SMN1; SMN2AKR1C1TSHRAPOBEC3AAPOBEC3G
SCHEMBL14967944 0.83 MAPT (0.36) SMN1; SMN2OPRM1ALDH1A1
SCHEMBL14967508 0.82 CYP3A4 (0.41) SMN1; SMN2KMT2AALDH1A1
SCHEMBL14968200 0.81 SLC6A4 (0.42) SMN1; SMN2ALDH1A1
SCHEMBL14968268 0.81 MEN1 (0.46) SMN1; SMN2AKR1C1TSHRAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed