SCHEMBL14968268

SCHEMBL14968268

COC(=O)C1(c2ccccc2)OC12CCCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
AKR1C1 Q04828 1/20 0.42
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HDAC4 P56524 2/20 0.41
CHRM3 P20309 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 1/20 0.39
APOBEC3A P31941 2/20 0.39
APOBEC3G Q9HC16 2/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
GAA P10253 1/20 0.38
PRCP P42785 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967505 0.98 MEN1 (0.45) MEN1KMT2AAKR1C1HTTL3MBTL1
SCHEMBL14968183 0.97 MEN1 (0.46) MEN1KMT2AAKR1C1HTTL3MBTL1
SCHEMBL14968327 0.86 CYP3A4 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL14967509 0.85 KDM4E (0.46) KMT2AL3MBTL1ALDH1A1CYP3A4GAA
SCHEMBL14966832 0.85 CYP3A4 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL14968070 0.84 CHRM3 (0.49) MEN1KMT2AAKR1C1HTTL3MBTL1
SCHEMBL14966595 0.84 AKR1C1 (0.39) MEN1KMT2AAKR1C1HTTHDAC4
SCHEMBL16110026 0.84 OPRM1 (0.51) MEN1KMT2ACYP3A4PRCPSIGMAR1
SCHEMBL14967750 0.84 SLC6A4 (0.46) MEN1KMT2AALDH1A1CYP3A4GAA
SCHEMBL14967459 0.84 APOBEC3A (0.45) AKR1C1HTTHDAC4CHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed