SCHEMBL8023632

SCHEMBL8023632

[C-]#[N+]C1CCC(P(=O)(c2ccccc2)C2CCC([N+]#[C-])CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA5A P35218 1/20 0.33
CFTR P13569 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966174 0.84 CA2 (0.44) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL14966208 0.77 GAA (0.44) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL14966930 0.77 GAA (0.44) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL8148549 0.76 SMYD3 (0.39) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL778386 0.75 SMN1; SMN2 (0.43) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL8597062 0.70 ALDH1A1 (0.39) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL10426380 0.68 SMN1; SMN2 (0.52) GAASMN1; SMN2CA2CA4CA5A
SCHEMBL24899679 0.65 CYP2A6 (0.36)
SCHEMBL24782522 0.65 HPGD (0.50) GAASMN1; SMN2
SCHEMBL24899752 0.65 EPHX1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6106523-A A SURGICAL INSTRUMENT COMPRISING A THERMALLY SPRAYED CERAMIC COATINGS ON THE ROUGHENED METAL SUBSTRATE AND A POLYESTERURETHANE COPOLYMER OVERCOATINGS; PROTECTIVE COATINGS; DIELECTRIC MEDICOR CORPORATION (US) 2000-08-22 US disclosed
WO-2000045728-A1 IMPLEMENTS WITH COMPOSITE COATING MEDICOR CORPORATION (US) 2000-08-10 WO disclosed
EP-0670756-A4 WATER-BORNE COMPOSITIONS COMPRISING HALF ESTERS OF ANHYDRIDE POLYMERS CROSSLINKED BY EPOXIES. DU PONT (US) 1996-08-21 EP disclosed
EP-0669955-A4 AN ANHYDRIDE-EPOXY COATING COMPOSITION MODIFIED WITH A SILANE POLYMER. DU PONT (US) 1996-08-07 EP disclosed
EP-0669954-A4 AN ACID-EPOXY-MELAMINE COATING COMPOSITION MODIFIED WITH A SILANE POLYMER. DU PONT (US) 1995-11-08 EP disclosed
EP-0670756-A1 WATER-BORNE COMPOSITIONS COMPRISING HALF ESTERS OF ANHYDRIDE POLYMERS CROSSLINKED BY EPOXIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-13 EP disclosed
EP-0669955-A1 AN ANHYDRIDE-EPOXY COATING COMPOSITION MODIFIED WITH A SILANE POLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-06 EP disclosed
EP-0669954-A1 AN ACID-EPOXY-MELAMINE COATING COMPOSITION MODIFIED WITH A SILANE POLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-06 EP disclosed
US-5376706-A Clear protective coatings E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-27 US disclosed
US-5376704-A Clearcoats with improved environmental resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-27 US disclosed
US-4243573-A Acrylic graft copolymers and coating compositions thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-06 US disclosed
US-4206108-A GRAFTED WITH DIISOCYANATE-MERCAPTOALKANOL ADDUCT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-06-03 US disclosed
US-4206294-A ALLYL ALCOHOL-STYRENE COPOLYMER, MERCAPTOISOCYANATE, POLYACRYLATE SIDE CHAINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-06-03 US disclosed
WO-1980001071-A1 CATIONIC COATING COMPOSITIONS GROW GROUP INC (US) 1980-05-29 WO disclosed
US-4186117-A Cathodic electrodeposition coating compositions containing diels-alder adducts GROW CHEMICAL CORP. (US) 1980-01-29 US disclosed
US-4169955-A GRAFT POLYMER INTERMEDIATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-10-02 US disclosed
US-4155824-A ACRYLIC POLYMER CONTAINING OXIRANE GROUPS WHICH HAVE BEEN OPENED WITH A FATTY ACID AND AN AMINE GROW CHEMICAL CORP. (US) 1979-05-22 US disclosed
US-4151227-A Acrylic graft copolymers and coating compositions thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-24 US disclosed
US-4148704-A ADHESION, CORROSION RESISTANCE, GLOSS GROW CHEMICAL CORP. (US) 1979-04-10 US disclosed
US-3969569-A ALLYL ALCOHOL POLYMER AND A POLYISOCYANATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 US disclosed