SCHEMBL14967013

SCHEMBL14967013

CCCCOC(=O)C1(c2ccc(OC)cc2)OC1c1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.41
ALDH1A1 P00352 8/20 0.40
GAA P10253 3/20 0.40
LMNA P02545 2/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 4/20 0.38
TSHR P16473 3/20 0.38
MEN1 O00255 3/20 0.38
POLB P06746 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967096 0.97 MIF (0.39) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL14967655 0.96 HSD17B10 (0.39) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL16109608 0.95 ALDH1A1 (0.40) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL14967936 0.95 ALDH1A1 (0.40) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL14967701 0.94 SIGMAR1 (0.42) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL16109040 0.93 ALDH1A1 (0.39) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL16108696 0.92 HSD17B10 (0.39) MIFALDH1A1GAALMNAHSD17B10
SCHEMBL16109499 0.92 SIGMAR1 (0.41) MIFALDH1A1LMNASIGMAR1CHRM1
SCHEMBL16109557 0.91 PPARG (0.42) ALDH1A1LMNAHSD17B10KDM4ESIGMAR1
SCHEMBL16109754 0.90 ALDH1A1 (0.40) ALDH1A1GAALMNAHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed