SCHEMBL14967701

SCHEMBL14967701

CCCCOC(=O)C1(c2ccccc2)OC1c1ccc(OC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.42
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
ALDH1A1 P00352 7/20 0.40
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MIF P14174 1/20 0.39
CACNA1D Q01668 1/20 0.39
EDNRA P25101 2/20 0.39
EDNRB P24530 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
RECQL P46063 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109499 0.98 SIGMAR1 (0.41) SIGMAR1CHRM5CHRM1CHRM3ALDH1A1
SCHEMBL16109557 0.97 PPARG (0.42) SIGMAR1CHRM5CHRM1CHRM3ALDH1A1
SCHEMBL14968112 0.95 CHRM5 (0.41) SIGMAR1CHRM5CHRM1CHRM3ALDH1A1
SCHEMBL14967013 0.94 MIF (0.41) SIGMAR1CHRM1ALDH1A1TSHRTDP1
SCHEMBL14967096 0.92 MIF (0.39) SIGMAR1CHRM1ALDH1A1TSHRMIF
SCHEMBL14967448 0.91 TSHR (0.44) SIGMAR1CHRM5CHRM1CHRM3ALDH1A1
SCHEMBL14967655 0.91 HSD17B10 (0.39) SIGMAR1ALDH1A1TSHRMIFKDM4E
SCHEMBL14967931 0.90 ALDH1A1 (0.46) ALDH1A1TSHRCACNA1DEDNRAEDNRB
SCHEMBL16109608 0.89 ALDH1A1 (0.40) SIGMAR1CHRM1ALDH1A1TSHRMIF
SCHEMBL16109789 0.89 TSHR (0.40) ALDH1A1TSHRTDP1L3MBTL1CACNA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed