SCHEMBL14967936

SCHEMBL14967936

CCCOC(=O)C1(c2ccc(OC)cc2)OC1c1ccc(OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
GAA P10253 3/20 0.40
LMNA P02545 2/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
SIGMAR1 Q99720 2/20 0.37
MIF P14174 1/20 0.36
DRD2 P14416 1/20 0.35
HSD11B1 P28845 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109754 0.95 ALDH1A1 (0.40) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL14967013 0.95 MIF (0.41) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL14968112 0.94 CHRM5 (0.41) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL14967096 0.93 MIF (0.39) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL14967655 0.91 HSD17B10 (0.39) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL16109608 0.90 ALDH1A1 (0.40) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL14967368 0.90 ALDH1A1 (0.48) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL14967701 0.89 SIGMAR1 (0.42) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL16109040 0.88 ALDH1A1 (0.39) ALDH1A1GAALMNAHSD17B10HPGD
SCHEMBL16108696 0.87 HSD17B10 (0.39) ALDH1A1GAALMNAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed