SCHEMBL14967183

SCHEMBL14967183

CCCCOC(=O)C12CCCCC1O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
LMNA P02545 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 2/20 0.38
ABCB11 O95342 1/20 0.38
CYP1A2 P05177 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38
CYP2C9 P11712 1/20 0.38
CHRM3 P20309 1/20 0.38
DRD1 P21728 1/20 0.38
HRH2 P25021 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
SCN1A P35498 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967554 0.99 CYP3A4 (0.40) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14967962 0.96 PRKCA (0.38) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14968001 0.95 LMNA (0.38) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14967471 0.94 CYP3A4 (0.39) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14967753 0.94 PRKCA (0.40) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14967517 0.93 PRKCA (0.39) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14967690 0.91 PRKCA (0.39) LMNATSHRMAPK1POLBSMN1; SMN2
SCHEMBL14967438 0.91 CYP3A4 (0.40) CYP3A4LMNAHSD17B10TSHRABCB11
SCHEMBL14967974 0.90 PRKCA (0.40) TSHRMAPK1SMN1; SMN2PRKCA
SCHEMBL14967412 0.90 CYP3A4 (0.42) CYP3A4LMNAHSD17B10TSHRABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
CN-105505526-B Phosphate hydraulic fluid hydrolysis stability reinforcing agent and phosphate hydraulic fluid composition containing same 中国石油化工股份有限公司 2020-03-31 CN disclosed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed