SCHEMBL14967753

SCHEMBL14967753

CCCCCCOC(=O)C12CCCCC1O2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.40
NAAA Q02083 3/20 0.39
MAPK1 P28482 2/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CES2 O00748 1/20 0.38
EPHX1 P07099 1/20 0.37
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
ABCB11 O95342 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM1 P11229 1/20 0.36
CYP2C9 P11712 1/20 0.36
CHRM3 P20309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967517 0.99 PRKCA (0.39) PRKCANAAAMAPK1GAAHTT
SCHEMBL14967962 0.99 PRKCA (0.38) PRKCANAAAMAPK1GAAHTT
SCHEMBL14967471 0.97 CYP3A4 (0.39) PRKCANAAAMAPK1GAAHTT
SCHEMBL14967974 0.96 PRKCA (0.40) PRKCANAAAMAPK1GAAHTT
SCHEMBL14967690 0.94 PRKCA (0.39) PRKCANAAAMAPK1GAAHTT
SCHEMBL14967183 0.94 CYP3A4 (0.38) PRKCAMAPK1SMN1; SMN2TSHRCYP3A4
SCHEMBL14967554 0.93 CYP3A4 (0.40) PRKCANAAAMAPK1SMN1; SMN2TSHR
SCHEMBL14968001 0.90 LMNA (0.38) PRKCANAAAMAPK1SMN1; SMN2TSHR
SCHEMBL14967438 0.88 CYP3A4 (0.40) MAPK1SMN1; SMN2TSHRCYP3A4ABCB11
SCHEMBL14967412 0.87 CYP3A4 (0.42) MAPK1SMN1; SMN2TSHRCYP3A4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
CN-105505526-B Phosphate hydraulic fluid hydrolysis stability reinforcing agent and phosphate hydraulic fluid composition containing same 中国石油化工股份有限公司 2020-03-31 CN disclosed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed