SCHEMBL14967974

SCHEMBL14967974

CCCCCCOC(=O)C12CCCC1O2

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 7/20 0.40
NAAA Q02083 1/20 0.40
CES2 O00748 1/20 0.39
EPHX1 P07099 1/20 0.38
TSHR P16473 2/20 0.37
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967690 0.99 PRKCA (0.39) PRKCANAAACES2EPHX1TSHR
SCHEMBL14967753 0.96 PRKCA (0.40) PRKCANAAACES2EPHX1TSHR
SCHEMBL14967517 0.94 PRKCA (0.39) PRKCANAAACES2EPHX1TSHR
SCHEMBL14967962 0.94 PRKCA (0.38) PRKCANAAACES2EPHX1TSHR
SCHEMBL14968001 0.94 LMNA (0.38) PRKCANAAATSHRMAPK1SMN1; SMN2
SCHEMBL14967471 0.93 CYP3A4 (0.39) PRKCANAAACES2EPHX1TSHR
SCHEMBL14967183 0.90 CYP3A4 (0.38) PRKCATSHRMAPK1SMN1; SMN2
SCHEMBL14967554 0.89 CYP3A4 (0.40) PRKCANAAATSHRMAPK1SMN1; SMN2
SCHEMBL14968098 0.88 PPM1B (0.36) TSHRGAAMAPK1SMN1; SMN2
SCHEMBL14967438 0.84 CYP3A4 (0.40) TSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed