SCHEMBL14967334

SCHEMBL14967334

CCC1(C(=O)Oc2ccccc2)OC1c1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
MAPT P10636 4/20 0.36
CACNA1D Q01668 1/20 0.36
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 1/20 0.35
PTK2B Q14289 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967898 0.92 MAPT (0.39) MAPTPOLBL3MBTL1TSHR
SCHEMBL16109777 0.88 EDNRA (0.41) MAOBMAPTCACNA1DL3MBTL1LMNA
SCHEMBL16109082 0.82 USP2 (0.42) USP2MAOAMAOBMAPTPOLB
SCHEMBL14967634 0.82 OPRM1 (0.39) MAPTCACNA1DLMNAGAATSHR
SCHEMBL14968220 0.82 CYP3A4 (0.36) MAOBCACNA1DPOLBLMNAGAA
SCHEMBL14967143 0.79 TSHR (0.48) CACNA1DGAATSHR
SCHEMBL14966700 0.78 ALDH1A1 (0.34) MAPTCACNA1DPOLBLMNATSHR
SCHEMBL16110596 0.78 ADORA2B (0.33) CACNA1DLMNA
SCHEMBL14967023 0.78 ABHD10 (0.41) MAPTCACNA1DLMNAGAA
SCHEMBL14968287 0.77 MAPT (0.41) MAPTPOLBLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed