SCHEMBL14967437

SCHEMBL14967437

CCCCOC(=O)C1OC1(CC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.44
TSHR P16473 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
PPARG P37231 3/20 0.43
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 3/20 0.41
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 1/20 0.40
TP53 P04637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
BCHE P06276 1/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39
CHRM5 P08912 2/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
HPGD P15428 1/20 0.39
ATM Q13315 1/20 0.39
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967067 0.96 PPARG (0.48) L3MBTL1TSHRTDP1PPARGALDH1A1
SCHEMBL14967318 0.95 PPARG (0.50) L3MBTL1TSHRTDP1PPARGALDH1A1
SCHEMBL14967754 0.92 LMNA (0.44) TSHRPPARGALDH1A1LMNACHRM2
SCHEMBL16108654 0.88 TSHR (0.37) L3MBTL1TSHRTDP1PPARGALDH1A1
SCHEMBL14967638 0.87 MIF (0.41) L3MBTL1TSHRTDP1ALDH1A1MAPK1
SCHEMBL14967939 0.86 TSHR (0.48) L3MBTL1TSHRALDH1A1KDM4ECYP2C19
SCHEMBL14967743 0.85 MIF (0.39) TSHRPPARGALDH1A1MAPK1CYP3A4
SCHEMBL16109650 0.84 PPARG (0.39) TSHRPPARGALDH1A1MAPK1CYP3A4
SCHEMBL14968175 0.84 PPARG (0.39) TSHRPPARGALDH1A1TP53LMNA
SCHEMBL14967420 0.83 TSHR (0.46) L3MBTL1TSHRTDP1PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed