SCHEMBL14967754

SCHEMBL14967754

CCCOC(=O)C1OC1(CC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.41
NPSR1 Q6W5P4 1/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
HCAR3 P49019 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
PPARG P37231 3/20 0.36
TSHR P16473 1/20 0.36
PRCP P42785 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967437 0.92 L3MBTL1 (0.44) LMNAALDH1A1NPSR1CHRM2CHRM4
SCHEMBL14967067 0.91 PPARG (0.48) LMNAALDH1A1SMN1; SMN2CHRM2CHRM4
SCHEMBL14967318 0.89 PPARG (0.50) LMNAALDH1A1NPSR1SMN1; SMN2CHRM2
SCHEMBL14967939 0.88 TSHR (0.48) ALDH1A1GAAHCAR3HCAR2TSHR
SCHEMBL16110563 0.87 ALDH1A1 (0.34) LMNAALDH1A1GAASMN1; SMN2CHRM1
SCHEMBL14967899 0.85 CHRM2 (0.37) LMNAALDH1A1GAASMN1; SMN2CHRM2
SCHEMBL9692301 0.84 HTT (0.45) ALDH1A1HCAR3HCAR2TSHR
SCHEMBL14967217 0.82 LMNA (0.46) LMNAALDH1A1NPSR1GAASMN1; SMN2
SCHEMBL14967077 0.81 LMNA (0.45) LMNAALDH1A1NPSR1GAASMN1; SMN2
SCHEMBL14967432 0.81 ELANE (0.38) ALDH1A1GAACHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed