SCHEMBL14967644

SCHEMBL14967644

CCCCOC(=O)C1(c2ccc(C)cc2)OC12CCCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 2/20 0.38
RAB9A P51151 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
PRCP P42785 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
GAA P10253 2/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968056 0.99 KMT2A (0.42) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967982 0.97 KMT2A (0.40) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967380 0.96 MEN1 (0.40) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967811 0.95 MEN1 (0.39) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967924 0.95 MEN1 (0.39) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14968254 0.94 MEN1 (0.38) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967346 0.94 OPRM1 (0.38) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967857 0.93 ALDH1A1 (0.38) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967378 0.92 ALDH1A1 (0.42) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967561 0.91 ALDH1A1 (0.41) KMT2AMEN1OPRM1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed