SCHEMBL14967982

SCHEMBL14967982

CCCCOC(=O)C1(c2ccc(C)cc2)OC12CCC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MAPT P10636 3/20 0.36
CNR2 P34972 2/20 0.36
RAB9A P51151 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967644 0.97 KMT2A (0.43) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14967346 0.96 OPRM1 (0.38) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14968056 0.96 KMT2A (0.42) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14967857 0.95 ALDH1A1 (0.38) KMT2AMEN1OPRM1ALDH1A1MAPT
SCHEMBL14967380 0.94 MEN1 (0.40) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14967924 0.93 MEN1 (0.39) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14967811 0.93 MEN1 (0.39) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14967956 0.92 OPRM1 (0.40) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14968254 0.92 MEN1 (0.38) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2
SCHEMBL14967378 0.90 ALDH1A1 (0.42) KMT2AMEN1OPRM1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed