SCHEMBL14967650

SCHEMBL14967650

CCCCCOC(=O)C1(C)CO1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
NAAA Q02083 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CES2 O00748 1/20 0.44
PSEN1 P49768 3/20 0.43
EPHX1 P07099 1/20 0.43
HCAR2 Q8TDS4 2/20 0.41
PRKCA P17252 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11158310 0.98 TSHR (0.49) TSHRNAAAALDH1A1CES2PSEN1
SCHEMBL14967788 0.98 TSHR (0.49) TSHRNAAAALDH1A1CES2PSEN1
SCHEMBL3807047 0.94 ALDH1A1 (0.52) TSHRNAAAALDH1A1CES2PSEN1
SCHEMBL3043065 0.94 ALDH1A1 (0.52) TSHRNAAAALDH1A1CES2PSEN1
SCHEMBL1728051 0.86 SMN1; SMN2 (0.36) TSHRALDH1A1CES2PSEN1HCAR2
SCHEMBL5075328 0.86 NAAA (0.43) TSHRNAAAALDH1A1CES2PSEN1
SCHEMBL18679883 0.81 TSHR (0.46) TSHRNAAAALDH1A1CES2EPHX1
SCHEMBL19367024 0.81 TSHR (0.46) TSHRNAAAALDH1A1CES2EPHX1
SCHEMBL14967582 0.80 CES2 (0.47) TSHRNAAAALDH1A1CES2PSEN1
SCHEMBL5072698 0.80 ALDH1A1 (0.44) TSHRNAAAALDH1A1PSEN1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109100918-B Photosensitive resin composition and preparation method and application thereof 深圳市华星光电技术有限公司 2020-08-04 CN disclosed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed