SCHEMBL1728051

SCHEMBL1728051

CCCOC(=O)C1(C)CO1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HCAR2 Q8TDS4 1/20 0.35
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
LMNA P02545 1/20 0.33
PSEN1 P49768 3/20 0.33
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
TSHR P16473 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ATM Q13315 1/20 0.32
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3043065 0.88 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1HCAR2LMNAPSEN1
SCHEMBL3807047 0.88 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1HCAR2LMNAPSEN1
SCHEMBL14967650 0.86 TSHR (0.46) ALDH1A1HCAR2PSEN1TSHRCES2
SCHEMBL14967788 0.85 TSHR (0.49) ALDH1A1HCAR2PSEN1TSHRCES2
SCHEMBL11158310 0.85 TSHR (0.49) ALDH1A1HCAR2PSEN1TSHRCES2
SCHEMBL9206727 0.83
SCHEMBL20261666 0.80 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1HCAR2PPM1BPTPN1
SCHEMBL16882926 0.78
SCHEMBL14968089 0.78 LMNA (0.38) ALDH1A1HCAR2PPM1BPTPN1PPP1CC
SCHEMBL20414494 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103890659-A Photopolymerizable unsaturated resin, photosensitive resin composition containing the same, and light-shielding spacer and liquid crystal display device prepared therefrom ROHM & HAAS ELECT MAT 2014-06-25 CN claimed
CN-1107492-C Improvements in or relating to polymerizable cementing compositions DAVIS SCHOTTLANDER & DAVIS LTD (GB) 2003-05-07 CN claimed
CN-1243429-A Improvements in or relating to polymerizable cementing compositions DAVIS SCHOTTLANDER & DAVIS LTD (GB) 2000-02-02 CN claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2810987-B1 EPOXY RESIN COMPOSITION AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2016-03-30 EP disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20150065606-A1 EPOXY RESIN COMPOSITION AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-03-05 US disclosed
EP-2810987-A1 EPOXY RESIN COMPOSITION AND FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2014-12-10 EP disclosed
US-6057265-A A HEAT RESISTANT LUBRICATING LAYER COMPRISING A POLYETHERSILOXANE COPOLYMER HAVING HEAT RESISTANCE AND LUBRICITY, EXCELLENT IN RUNNING STABILITY IN RECORDING, AND EXHIBITING AN EXCELLENT STORAGE STABILITY MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2000-05-02 US disclosed
CN-1243429-A Improvements in or relating to polymerizable cementing compositions DAVIS SCHOTTLANDER & DAVIS LTD (GB) 2000-02-02 CN disclosed
EP-0564583-B1 METHOD FOR TINTING A HYDROPHILIC POLYMER ALLERGAN INC (US) 1995-11-15 EP disclosed
EP-0564583-A4 ALLERGAN INC (US) 1994-01-19 EP disclosed
EP-0564583-A1 METHOD FOR TINTING A HYDROPHILIC POLYMER. ALLERGAN INC (US) 1993-10-13 EP disclosed
US-5151106-A Mixing a dichlorotriazine reactive polymer and reaction with polymer in the presence of a catalyst and molding to form contact lenses ALLERGAN, INC. (US) 1992-09-29 US disclosed
WO-1992011407-A1 METHOD FOR TINTING A HYDROPHILIC POLYMER ALLERGAN, INC. (US) 1992-07-09 WO disclosed
US-4985145-A Reverse osmosis; polyelectrolyte layer formed on hydrated metal oxide coated membrane WATER RESEARCH COMMISSION (ZA) 1991-01-15 US disclosed
US-4263394-A Aqueous alkaline soluble photopolymerizable material VICKERS LIMITED (GB) 1981-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 SMN1; SMN2 4707/4885ALDH1A1 1061/4885HCAR2 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.